A look at what's happening all around the major leagues Wednesday:
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RIB CHECK
Blue Jays shortstop Jose Reyes will take batting practice for first time since cracking a rib on April 27. Reyes is eligible to come off the disabled list Wednesday but still must go on a brief rehab assignment, manager John Gibbons said.
CY YOUNG WINNER NEEDS A WIN
Indians right-hander Corey Kluber is still looking for his first win of the season. The reigning AL Cy Young Award winner is 0-5 with a 5.04 ERA, and the Indians have lost all seven of his starts. Opponents are batting .290 against him after hitting .233 last season, when Kluber was 18-9 with a 2.44 ERA.
LEFT OUT
The Pirates will face a left-handed starter for just the fourth time when they oppose Philadelphia ace Cole Hamels (2-3, 3.68). No team in the majors has faced fewer lefties than Pittsburgh.
BEEN AROUND
Cardinals right-hander John Lackey will make his 309th career start against an American League team when he takes the mound against the Indians. He's 131-105 vs. the AL, including 8-8 in 20 starts against Cleveland. Lackey pitched for the Angels and Red Sox before being traded to St. Louis last July.
AS ADVERTISED
James Shields tries to open 5-0 in his first season with the San Diego Padres when he pitches at Seattle in an interleague game between teams that share a spring training complex in Arizona. On the mound for the Mariners is touted youngster Taijuan Walker, off to a disappointing start at 1-3 with an 8.13 ERA.
WELCOME BACK
Houston left-hander Brett Oberholtzer is set to make his season debut against San Francisco. Oberholtzer was projected as the team's No. 3 starter before developing a blister on his index finger. Also, outfielder George Springer is eligible to come off the seven-day concussion disabled list for the Astros.