Harvin was listed doubtful on Friday after missing another week of practice, and the team downgraded him to out on the injury report Saturday while deciding not to take him on the trip so he can continue to rest.
Harvin was hurt Nov. 4 at Seattle and missed the Nov. 11 game against Detroit. The Vikings had a bye last week.
Harvin is tied for 10th in the NFL with 62 receptions. He entered the week second in the league behind Green Bay's Randall Cobb in total yards, including receiving, rushing and returning.