CHICAGO -- Jake Arrieta allowed three hits over seven innings and Starlin Castro had a go-ahead RBI single in a two-run seventh, leading the Chicago Cubs over the St. Louis Cardinals 2-0 Wednesday for their first win this season.
Backed by just two hits from Chicago's offense, Arrieta (1-0) struck out seven and walked three. Phil Coke, Neil Ramirez, Pedro Strop and Hector Rondon combined for hitless relief.
Rendon pitched a perfect ninth for his first save with the Cubs, who lost 3-0 to St. Louis on Sunday night's opener.
Lance Lynn (0-1) struck out nine in six-plus innings, allowing both runs -- one earned -- and two hits.
TIGERS 11, TWINS 0
DETROIT -- Anibal Sanchez helped Detroit blank Minnesota for the second straight game, Jose Iglesias had four hits and Alex Avila scored four runs.
Ian Kinsler drove in four runs for Detroit, which had beaten Minnesota 4-0 on opening day. Sanchez (1-0) allowed three hits and two walks in 6 2-3 innings while striking out six.
Ricky Nolasco (0-1) gave up six runs and six hits in three-plus innings, walked four and struck out two.
BRAVES 2, MARLINS 0
MIAMI -- A.J. Pierzynski hit a two-run homer and five pitchers combined on a six-hitter to help Atlanta complete a three-game sweep.
The season-opening sweep was the first for the Braves since 2007, and they outscored Miami 16-3 in the series.
The 38-year-old Pierzynski, playing in his first game with his newest team, broke up a scoreless tie in the seventh inning against Tom Koehler (0-1).
Shelby Miller made his first start with the Braves and allowed four hits in five innings. Brandon Cunniff (1-0) followed with 1 2-3 perfect innings for his first major-league victory. Jason Grilli pitched a 1-2-3 ninth for his second save.
PHILLIES 4, RED SOX 2
PHILADELPHIA -- Jeff Francoeur hit a three-run homer, and Aaron Harang (1-0) took a one-hitter into the seventh inning.
Making his Red Sox debut after signing an $82.5 million, four-year contract through 2019, Rick Porcello (0-1) allowed three runs and six hits in six innings.
Harang gave up two hits, walked one and struck out eight in 6 1-3 innings in his first start for the Phillies. Jonathan Papelbon got four outs against his former team for his first save.
Francoeur went deep for the first time in two years for Philadelphia's first runs this season.
YANKEES 4, BLUE JAYS 3
NEW YORK -- Chase Headley hit a tiebreaking single that deflected off the wrist of reliever Brett Cecil as New York rallied for three runs in the eighth inning.
Pinch-hitter Chris Young opened the eighth with a bloop double that eluded rookie second baseman Devon Travis, Jacoby Ellsbury singled, and Aaron Loup (0-1) loaded the bases when he hit Brett Gardner with a pitch.
Young scored on a wild pitch by Cecil, who forced in the tying run when he plunked McCann with a pitch. Headley hit a one-hopper that caromed off Cecil's right wrist and past shortstop.
Dellin Betances (1-0) got the win and Andrew Miller worked a perfect ninth for the save in his Yankees debut. The crowd of 31,020 was New York's smallest for a home game in 11 years.
NATIONALS 2, METS 1
WASHINGTON -- Jordan Zimmermann (1-0) didn't quite pick up where he left off in 2014, when he threw a no-hitter to close the regular season, but he only allowed one run in six innings.
Ryan Zimmerman hit a two-run homer in the first off NL Rookie of the Year Jacob deGrom (0-1).
Closer Drew Storen had a 1-2-3 ninth for his first save.
RAYS 2, ORIOLES 0
ST. PETERSBURG, Fla. -- Jake Odorizzi (1-0) allowed two hits and struck out seven in 6 2-3 innings, and Tampa Bay coaxed four consecutive walks with two outs to score the go-ahead run.
Baltimore's Miguel Gonzalez (0-1) retired the first two batters in the Rays sixth, then walked Evan Longoria and Desmond Jennings. Pinch-hitter Brandon Guyer and Logan Forsythe drew walks from Brian Matusz to give the Rays their first lead of the year.
Jeff Beliveau, Kevin Jepsen and Brad Boxberger finished the three-hitter as the Rays gave rookie manager Kevin Cash his first victory and avoided being swept in the opening series at Tropicana Field.
INDIANS 2, ASTROS 0
HOUSTON -- Carlos Carrasco struck out 10 while pitching three-hit ball into the seventh inning, Carlos Santana and Mike Aviles each homered and the Indians got a win over the Astros.
Carrasco (1-0) walked one in 6 1-3 innings a day after signing a four-year contract.
Santana put Cleveland up with his homer in the fourth inning and Aviles added an insurance run with his home run to the Crawford Boxes in left field in the eighth.
Cody Allen pitched a perfect ninth for his first save.
Houston starter Scott Feldman (0-1) yielded five hits and a run in 6 2-3 innings in the loss.
ROYALS 7, WHITE SOX 5
KANSAS CITY, Mo. -- Lorenzo Cain hit a go-ahead two-run homer in the eighth inning for his third hit and the Royals beat the White Sox.
Cain homered off Zach Putnam (0-1), the fourth White Sox pitcher, after Alcides Escobar led off the inning with a single for his third hit.
Wade Davis (1-0) struck out two in a scoreless eighth. Greg Holland, who had 46 saves last year, worked the ninth for his first save.
Eric Hosmer hit a three-run homer in the third for the Royals.
ROCKIES 5, BREWERS 4, 10 INNINGS
MILWAUKEE -- Pinch-hitter Wilin Rosario homered in the 10th inning after being scratched from the starting lineup, leading the Rockies to a win over the Brewers.
Rosario initially was in the Rockies' batting order in place of Justin Morneau, who was hit in the neck by a ball while running the bases on Tuesday night. Morneau took batting practice and talked his way into the lineup, sending Rosario to the bench for the third straight game.
The big right-handed hitter, however, hit a full-count pitch from Milwaukee closer Francisco Rodriguez (0-1) over the wall in center field, giving the Rockies a three-game sweep in the season-opening series.
Colorado closer LaTroy Hawkins (1-0) got the win despite giving up a pair of runs in the ninth to send the game into extra innings.