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Eric Reid: Peyton Manning like a coordinator on the field

Observed and heard in the locker room after the San Francisco 49ers' 42-17 loss to the Denver Broncos:

  • The 49ers’ top two centers entering the game both left with injuries. Starter Daniel Kilgore suffered what coach Jim Harbaugh said “might be a break” in his lower left leg while backup Dillon Farrell, who limped off the field after replacing Kilgore, was seen walking around without a noticeable limp.

  • It was a stunned locker room, one that was trying to process how efficiently Peyton Manning dissected the 49ers' defense. “You’re playing against a coordinator out there,” free safety Eric Reid said of Manning.

  • The 49ers are beat up, both emotionally and physically after being run over by the Broncos. So, can the bye week come at a better time? “This is perfect timing,” linebacker Ahmad Brooks said.