ASHBURN, Va. -- Washington Redskins tight end Jordan Reed and nose tackle Chris Baker won’t play Sunday at San Francisco, but tackle Trent Williams still has a chance to play – though whether or not it’s realistic remains to be seen.

Williams said his sprained right knee was “getting better” and that he was somewhat optimistic about playing. But he was walking rather stiff-legged. He also hasn’t practiced this week. Williams is listed as questionable on the injury report.

“He’s made some progress in the training room,” Redskins coach Jay Gruden said. “There is a little more [optimism], but we’ll see how it goes. The five-hour flight and all that stuff, that will be a big deal, [if it] swells back up.”

On Monday, the Redskins held out little hope of Williams playing and they’re still preparing rookie Morgan Moses to make his first start.

Meanwhile, guard Shawn Lauvao also is questionable. He was limited again in practice Friday.

With Reed sidelined again – this will be the fifth game he’s missed this season – the bulk of the pass-catching duties at tight end fall on Niles Paul. He’s third on the team with 33 receptions and the 49ers have some weak spots in coverage at linebacker.

With Baker out, the Redskins likely will keep veteran Stephen Bowen active. He was inactive last week. It also means Barry Cofield will return to nose, one week after playing mostly in the nickel packages in his first game back from a high ankle sprain. Veteran Kedric Golston will be the backup nose tackle.

Baker injured his sternum vs. Tampa Bay and said Friday, "It's tough to lift your hands up, to reach across your body, breathe when you get tired. ... I should be OK next week."