Mike Wells, ESPN Staff Writer 9y

Prediction: Colts will beat the Giants

History is on quarterback Andrew Luck's side when it comes to back-to-back losses. He's only lost back-to-back games once - Weeks 1 and 2 this season - in 40 career regular-season NFL games.

The Indianapolis Colts can’t afford to lose to the Giants because they come out of their bye week having to face Tom Brady and the New England Patriots. Luck could have a full cupboard of offensive weapons to turn to, as running back Trent Richardson (hamstring) is expected to be back in the lineup and receiver Reggie Wayne (elbow) could be back.

The key is for Luck to avoid throwing interceptions. He's thrown nine this season, and the Giants are second in the league with 11 picks. Luck has thrown for at least 300 yards in six straight games. Combine that with the fact that the Giants are 25th in the league against the pass and that should equal success for him. Luck bounces back after throwing two picks last weekend against Pittsburgh and he adds on to his league-leading totals in passing yards and touchdowns. The Colts are second in the league in points a game (31.3) and the Giants are giving up more than 24 a game. The Colts won’t have any problems scoring points Monday.

Colts 35, Giants 20

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